Remimazolam for anaesthesia or sedation.
Curr Opin Anaesthesiol
; 33(4): 506-511, 2020 Aug.
Article
en En
| MEDLINE
| ID: mdl-32530890
ABSTRACT
PURPOSE OF REVIEW Anaesthesia and sedation are ubiquitous in contemporary medical practice. Developments in anaesthetic pharmacology are targeted on reducing physiological disturbance whilst maintaining or improving titrateability, recovery profile and patient experience. Remimazolam is a new short-acting benzodiazepine in the final stages of clinical development. RECENT FINDINGS:
Clinical experience with remimazolam comprises volunteer studies and a limited number of clinical investigations. In addition, laboratory investigations explore the implications of its 'soft drug' pharmacology.SUMMARY:
Remimazolam provides effective procedural sedation with superior success rates and recovery profile when compared to midazolam. Comparisons with propofol are required. Preliminary studies suggest potential for using remimazolam as the hypnotic component of general anaesthesia. Definitive studies are awaited. As a benzodiazepine, remimazolam could be evaluated as an anticonvulsant and for intensive care sedation.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Benzodiazepinas
/
Hipnóticos y Sedantes
Límite:
Humans
Idioma:
En
Revista:
Curr Opin Anaesthesiol
Asunto de la revista:
ANESTESIOLOGIA
Año:
2020
Tipo del documento:
Article