Overexpression of I&#954;B&#945; in cardiomyocytes alleviates hydrogen peroxide-induced apoptosis and autophagy by inhibiting NF-&#954;B activation.

Han, Min; Chen, Xiao-Cui; Sun, Ming-Hui; Gai, Min-Tao; Yang, Yi-Ning; Gao, Xiao-Ming; Ma, Xiang; Chen, Bang-Dang; Ma, Yi-Tong

Overexpression of IκBα in cardiomyocytes alleviates hydrogen peroxide-induced apoptosis and autophagy by inhibiting NF-κB activation.

Han, Min; Chen, Xiao-Cui; Sun, Ming-Hui; Gai, Min-Tao; Yang, Yi-Ning; Gao, Xiao-Ming; Ma, Xiang; Chen, Bang-Dang; Ma, Yi-Tong.

Afiliación

Han M; Xinjiang Key Laboratory of Cardiovascular Disease Research, Clinical Medical Research Institute, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, PR China.
Chen XC; Department of Cardiology, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, PR China.
Sun MH; Xinjiang Key Laboratory of Cardiovascular Disease Research, Clinical Medical Research Institute, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, PR China.
Gai MT; Department of Nephrology, Fifth Affiliated Hospital of Xinjiang Medical University, Urumqi, 830000, PR China.
Yang YN; Xinjiang Key Laboratory of Cardiovascular Disease Research, Clinical Medical Research Institute, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, PR China.
Gao XM; Department of Cardiology, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, PR China.
Ma X; Xinjiang Key Laboratory of Cardiovascular Disease Research, Clinical Medical Research Institute, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, PR China.
Chen BD; Department of Cardiology, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, PR China.
Ma YT; Xinjiang Key Laboratory of Cardiovascular Disease Research, Clinical Medical Research Institute, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, PR China. chenbangdang@126.com.

Lipids Health Dis ; 19(1): 150, 2020 Jun 24.

Article en En | MEDLINE | ID: mdl-32580730

Asunto(s)

Peróxido de Hidrógeno/farmacología; Miocitos Cardíacos/patología; Inhibidor NF-kappaB alfa/genética; FN-kappa B/metabolismo; Animales; Apoptosis/efectos de los fármacos; Apoptosis/genética; Autofagia/efectos de los fármacos; Autofagia/genética; Células Cultivadas; Dependovirus/genética; Regulación de la Expresión Génica; Peróxido de Hidrógeno/metabolismo; Potencial de la Membrana Mitocondrial/efectos de los fármacos; Miocitos Cardíacos/efectos de los fármacos; Miocitos Cardíacos/metabolismo; Inhibidor NF-kappaB alfa/metabolismo; FN-kappa B/antagonistas & inhibidores; FN-kappa B/genética; Pirrolidinas/farmacología; Ratas Sprague-Dawley; Tiocarbamatos/farmacología; Transfección

Palabras clave

Adeno-associated virus serotype 9; Apoptosis; Autophagy; Cardiomyocytes; Inhibitor of kappa B alpha; Nuclear factor kappa B; Oxidative stress

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: FN-kappa B / Miocitos Cardíacos / Inhibidor NF-kappaB alfa / Peróxido de Hidrógeno Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Lipids Health Dis Asunto de la revista: BIOQUIMICA / METABOLISMO Año: 2020 Tipo del documento: Article

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