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Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease.
Elitt, Matthew S; Barbar, Lilianne; Shick, H Elizabeth; Powers, Berit E; Maeno-Hikichi, Yuka; Madhavan, Mayur; Allan, Kevin C; Nawash, Baraa S; Gevorgyan, Artur S; Hung, Stevephen; Nevin, Zachary S; Olsen, Hannah E; Hitomi, Midori; Schlatzer, Daniela M; Zhao, Hien T; Swayze, Adam; LePage, David F; Jiang, Weihong; Conlon, Ronald A; Rigo, Frank; Tesar, Paul J.
Afiliación
  • Elitt MS; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Barbar L; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Shick HE; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Powers BE; Ionis Pharmaceuticals, Carlsbad, CA, USA.
  • Maeno-Hikichi Y; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Madhavan M; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Allan KC; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Nawash BS; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Gevorgyan AS; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Hung S; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Nevin ZS; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Olsen HE; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Hitomi M; Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Schlatzer DM; Case Center for Proteomics and Bioinformatics, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Zhao HT; Ionis Pharmaceuticals, Carlsbad, CA, USA.
  • Swayze A; Ionis Pharmaceuticals, Carlsbad, CA, USA.
  • LePage DF; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Jiang W; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Conlon RA; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Rigo F; Ionis Pharmaceuticals, Carlsbad, CA, USA.
  • Tesar PJ; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA. paul.tesar@case.edu.
Nature ; 585(7825): 397-403, 2020 09.
Article en En | MEDLINE | ID: mdl-32610343
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína Proteolipídica de la Mielina / Enfermedad de Pelizaeus-Merzbacher / Modelos Animales de Enfermedad Límite: Animals Idioma: En Revista: Nature Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína Proteolipídica de la Mielina / Enfermedad de Pelizaeus-Merzbacher / Modelos Animales de Enfermedad Límite: Animals Idioma: En Revista: Nature Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos