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Compromised IGF signaling causes caspase-6 activation in Huntington disease.
Skotte, Niels Henning; Pouladi, Mahmoud A; Ehrnhoefer, Dagmar E; Huynh, Katie; Qiu, Xiaofan; Nielsen, Signe Marie Borch; Nielsen, Troels Tolstrup; Nørremølle, Anne; Hayden, Michael R.
Afiliación
  • Skotte NH; Centre for Molecular Medicine and Therapeutics (CMMT), Department of Medical Genetics, University of British Columbia, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada; Section of Neurogenetics, Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhag
  • Pouladi MA; Centre for Molecular Medicine and Therapeutics (CMMT), Department of Medical Genetics, University of British Columbia, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada.
  • Ehrnhoefer DE; Centre for Molecular Medicine and Therapeutics (CMMT), Department of Medical Genetics, University of British Columbia, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada.
  • Huynh K; Centre for Molecular Medicine and Therapeutics (CMMT), Department of Medical Genetics, University of British Columbia, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada.
  • Qiu X; Centre for Molecular Medicine and Therapeutics (CMMT), Department of Medical Genetics, University of British Columbia, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada.
  • Nielsen SMB; Section of Neurogenetics, Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark.
  • Nielsen TT; Neurogenetics Clinic & Research Lab, Danish Dementia Research Centre, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, Denmark.
  • Nørremølle A; Section of Neurogenetics, Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark.
  • Hayden MR; Centre for Molecular Medicine and Therapeutics (CMMT), Department of Medical Genetics, University of British Columbia, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada. Electronic address: mrh@cmmt.ubc.ca.
Exp Neurol ; 332: 113396, 2020 10.
Article en En | MEDLINE | ID: mdl-32622701

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factor I del Crecimiento Similar a la Insulina / Transducción de Señal / Enfermedad de Huntington / Caspasa 6 Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Exp Neurol Año: 2020 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factor I del Crecimiento Similar a la Insulina / Transducción de Señal / Enfermedad de Huntington / Caspasa 6 Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Exp Neurol Año: 2020 Tipo del documento: Article