Syk inhibitor attenuates inflammation in lupus mice from FcgRIIb deficiency but not in pristane induction: the influence of lupus pathogenesis on the therapeutic effect.

Issara-Amphorn, Jiraphorn; Somboonna, Naraporn; Pisitkun, Prapaporn; Hirankarn, Nattiya; Leelahavanichkul, Asada

Issara-Amphorn, Jiraphorn; Somboonna, Naraporn; Pisitkun, Prapaporn; Hirankarn, Nattiya; Leelahavanichkul, Asada.

Afiliación

Issara-Amphorn J; Medical Microbiology, Interdisciplinary and International Programme, Graduate School, Chulalongkorn University, Bangkok, Thailand.
Somboonna N; Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Pisitkun P; Department of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
Hirankarn N; Microbiome Research Unit for Probiotics in Food and Cosmetics, Chulalongkorn University, Bangkok, Thailand.
Leelahavanichkul A; Division of Allergy, Immunology, and Rheumatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Lupus ; 29(10): 1248-1262, 2020 Sep.

Article en En | MEDLINE | ID: mdl-32700597

Asunto(s)

Endotoxinas/toxicidad; Lupus Eritematoso Sistémico/genética; Animales; Citocinas/sangre; Modelos Animales de Enfermedad; Humanos; Inflamación; Ratones; Ratones Endogámicos C57BL; Receptores de IgG/deficiencia; Receptores de IgG/genética; Quinasa Syk/antagonistas & inhibidores

Palabras clave

(1â3)-ß-D-glucan; FcgRIIb-deficient mice; endotoxin; gut leakage; spleen tyrosine kinase; systemic lupus erythematosus

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endotoxinas / Lupus Eritematoso Sistémico Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Lupus Asunto de la revista: REUMATOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Tailandia

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google