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Metformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation.
Wang, Chengcheng; Zhang, Taiping; Liao, Quan; Dai, Menghua; Guo, Junchao; Yang, Xinyu; Tan, Wen; Lin, Dongxin; Wu, Chen; Zhao, Yupei.
Afiliación
  • Wang C; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
  • Zhang T; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
  • Liao Q; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
  • Dai M; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
  • Guo J; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
  • Yang X; Department of Etiology and Carcinogenesis, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
  • Tan W; Department of Etiology and Carcinogenesis, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
  • Lin D; Department of Etiology and Carcinogenesis, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. lindx@cicams.ac.cn.
  • Wu C; Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, 211166, China. lindx@cicams.ac.cn.
  • Zhao Y; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, 510060, China. lindx@cicams.ac.cn.
Protein Cell ; 12(2): 128-144, 2021 02.
Article en En | MEDLINE | ID: mdl-32737864
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Regulación Neoplásica de la Expresión Génica / Regulación hacia Arriba / Proteína Smad4 / Factor Nuclear 4 del Hepatocito / Metformina Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Protein Cell Asunto de la revista: BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Regulación Neoplásica de la Expresión Génica / Regulación hacia Arriba / Proteína Smad4 / Factor Nuclear 4 del Hepatocito / Metformina Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Protein Cell Asunto de la revista: BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: China