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Combining hypoxia-activated prodrugs and radiotherapy in silico: Impact of treatment scheduling and the intra-tumoural oxygen landscape.
Hamis, Sara; Kohandel, Mohammad; Dubois, Ludwig J; Yaromina, Ala; Lambin, Philippe; Powathil, Gibin G.
Afiliación
  • Hamis S; School of Mathematics and Statistics, University of St Andrews, St Andrews, Scotland.
  • Kohandel M; Department of Mathematics, College of Science, Swansea University, Swansea, Wales, United Kingdom.
  • Dubois LJ; Department of Applied Mathematics, University of Waterloo, Waterloo, Canada.
  • Yaromina A; The M-Lab, Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
  • Lambin P; The M-Lab, Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
  • Powathil GG; The M-Lab, Department of Precision Medicine, GROW - School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
PLoS Comput Biol ; 16(8): e1008041, 2020 08.
Article en En | MEDLINE | ID: mdl-32745136
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Profármacos / Hipoxia de la Célula / Microambiente Tumoral / Modelos Biológicos / Antineoplásicos Límite: Humans Idioma: En Revista: PLoS Comput Biol Asunto de la revista: BIOLOGIA / INFORMATICA MEDICA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Profármacos / Hipoxia de la Célula / Microambiente Tumoral / Modelos Biológicos / Antineoplásicos Límite: Humans Idioma: En Revista: PLoS Comput Biol Asunto de la revista: BIOLOGIA / INFORMATICA MEDICA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido