Pregnancy and Hymenoptera venom allergy.
Curr Opin Allergy Clin Immunol
; 20(5): 465-469, 2020 10.
Article
en En
| MEDLINE
| ID: mdl-32769711
ABSTRACT
PURPOSE OF REVIEW To evaluate the indication to perform venom immunotherapy (VIT) during pregnancy considering the risks of adverse events during the build-up phase or the maintenance phase and analyzing specific articles and guidelines on VIT. RECENT FINDINGS:
Only few studies treat this argument and literature only counts one recent study on the topic, whereas recent guidelines state the behavior to keep in pregnancy.SUMMARY:
Hymenoptera venom allergy (HVA) affects about 7.5% of the European population. VIT is the only effective disease-modifying treatment for patients presenting anaphylactic reactions. VIT counts several mechanisms of action, with the increase of IgG1 and IgG4 and a cytokine impairment inducing a Th2-Th1 shift. Pregnancy is a health condition where a Th2 profile is required to prevent fetal rejection, so VIT could be a problem for the fetus when started during pregnancy.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Venenos de Artrópodos
/
Desensibilización Inmunológica
/
Himenópteros
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Anafilaxia
/
Mordeduras y Picaduras de Insectos
Tipo de estudio:
Guideline
Límite:
Adult
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Aged
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Animals
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Child
/
Female
/
Humans
/
Middle aged
/
Pregnancy
Idioma:
En
Revista:
Curr Opin Allergy Clin Immunol
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
2020
Tipo del documento:
Article