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Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza.
Scott, Claire; Kankanala, Jayakanth; Foster, Toshana L; Goldhill, Daniel H; Bao, Peng; Simmons, Katie; Pingen, Marieke; Bentham, Matthew; Atkins, Elizabeth; Loundras, Eleni; Elderfield, Ruth; Claridge, Jolyon K; Thompson, Joseph; Stilwell, Peter R; Tathineni, Ranjitha; McKimmie, Clive S; Targett-Adams, Paul; Schnell, Jason R; Cook, Graham P; Evans, Stephen; Barclay, Wendy S; Foster, Richard; Griffin, Stephen.
Afiliación
  • Scott C; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, St James's University Hospital, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Kankanala J; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Foster TL; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Goldhill DH; School of Chemistry, Faculty of Mathematics and Physical Sciences, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Bao P; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, St James's University Hospital, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Simmons K; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Pingen M; Faculty of Medicine, Section of Virology, Imperial College, London, United Kingdom.
  • Bentham M; Faculty of Engineering and Physical Sciences, School of Physics and Astronomy, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Atkins E; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Loundras E; School of Chemistry, Faculty of Mathematics and Physical Sciences, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Elderfield R; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, St James's University Hospital, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Claridge JK; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, St James's University Hospital, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Thompson J; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Stilwell PR; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, St James's University Hospital, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Tathineni R; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • McKimmie CS; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, St James's University Hospital, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Targett-Adams P; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Schnell JR; Faculty of Medicine, Section of Virology, Imperial College, London, United Kingdom.
  • Cook GP; Department of Biochemistry, University of Oxford, Oxford, United Kingdom.
  • Evans S; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Barclay WS; School of Chemistry, Faculty of Mathematics and Physical Sciences, University of Leeds, Leeds, West Yorkshire, United Kingdom.
  • Foster R; Faculty of Medicine, Section of Virology, Imperial College, London, United Kingdom.
  • Griffin S; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, St James's University Hospital, University of Leeds, Leeds, West Yorkshire, United Kingdom.
PLoS Pathog ; 16(8): e1008716, 2020 08.
Article en En | MEDLINE | ID: mdl-32780760
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Rimantadina / Proteínas de la Matriz Viral / Gripe Humana / Subtipo H1N1 del Virus de la Influenza A / Zanamivir Límite: Humans Idioma: En Revista: PLoS Pathog Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Rimantadina / Proteínas de la Matriz Viral / Gripe Humana / Subtipo H1N1 del Virus de la Influenza A / Zanamivir Límite: Humans Idioma: En Revista: PLoS Pathog Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido