Joint testing of donor and recipient genetic matching scores and recipient genotype has robust power for finding genes associated with transplant outcomes.

Arthur, Victoria L; Guan, Weihua; Loza, Bao-Li; Keating, Brendan; Chen, Jinbo

Arthur, Victoria L; Guan, Weihua; Loza, Bao-Li; Keating, Brendan; Chen, Jinbo.

Afiliación

Arthur VL; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Guan W; Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota.
Loza BL; Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Keating B; Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Chen J; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Genet Epidemiol ; 44(8): 893-907, 2020 11.

Article en En | MEDLINE | ID: mdl-32783273

Asunto(s)

Prueba de Histocompatibilidad; Donantes de Tejidos; Trasplante; Simulación por Computador; Intervalos de Confianza; Análisis de Datos; Femenino; Frecuencia de los Genes/genética; Genotipo; Antígenos HLA/genética; Humanos; Masculino; Persona de Mediana Edad; Modelos Genéticos; Oportunidad Relativa; Polimorfismo de Nucleótido Simple/genética; Probabilidad

Palabras clave

genetic matching scores; joint testing; transplant genetics

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Donantes de Tejidos / Trasplante / Prueba de Histocompatibilidad Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Genet Epidemiol Asunto de la revista: EPIDEMIOLOGIA / GENETICA MEDICA Año: 2020 Tipo del documento: Article

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