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Pharmacokinetic Modeling of [18F]MC225 for Quantification of the P-Glycoprotein Function at the Blood-Brain Barrier in Non-Human Primates with PET.
García-Varela, Lara; Arif, Wejdan M; Vállez García, David; Kakiuchi, Takeharu; Ohba, Hiroyuki; Harada, Norihiro; Tago, Tetsuro; Elsinga, Philip H; Tsukada, Hideo; Colabufo, Nicola Antonio; Dierckx, Rudi A J O; van Waarde, Aren; Toyohara, Jun; Boellaard, Ronald; Luurtsema, Gert.
Afiliación
  • García-Varela L; Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
  • Arif WM; Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
  • Vállez García D; Department of Radiological Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
  • Kakiuchi T; Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
  • Ohba H; Central Research Laboratory, Hamamatsu Photonics KK, 5000 Hirakuchi, Hamakita, Hamamatsu, Shizuoka 434-8601, Japan.
  • Harada N; Central Research Laboratory, Hamamatsu Photonics KK, 5000 Hirakuchi, Hamakita, Hamamatsu, Shizuoka 434-8601, Japan.
  • Tago T; Central Research Laboratory, Hamamatsu Photonics KK, 5000 Hirakuchi, Hamakita, Hamamatsu, Shizuoka 434-8601, Japan.
  • Elsinga PH; Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan.
  • Tsukada H; Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
  • Colabufo NA; Central Research Laboratory, Hamamatsu Photonics KK, 5000 Hirakuchi, Hamakita, Hamamatsu, Shizuoka 434-8601, Japan.
  • Dierckx RAJO; Department of Pharmacy, University of Bari Aldo Moro, Bari 70121, Italy.
  • van Waarde A; Biofordrug, Spin-off Università degli Studi di Bari "A. Moro", via Dante 99, Triggiano, Bari 70019, Italy.
  • Toyohara J; Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
  • Boellaard R; Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
  • Luurtsema G; Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan.
Mol Pharm ; 17(9): 3477-3486, 2020 09 08.
Article en En | MEDLINE | ID: mdl-32787277
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Primates / Tetrahidronaftalenos / Radioisótopos de Flúor / Barrera Hematoencefálica / Miembro 1 de la Subfamilia B de Casetes de Unión a ATP / Radiofármacos / Isoquinolinas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Primates / Tetrahidronaftalenos / Radioisótopos de Flúor / Barrera Hematoencefálica / Miembro 1 de la Subfamilia B de Casetes de Unión a ATP / Radiofármacos / Isoquinolinas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos