ABHD11 maintains 2-oxoglutarate metabolism by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex.

Bailey, Peter S J; Ortmann, Brian M; Martinelli, Anthony W; Houghton, Jack W; Costa, Ana S H; Burr, Stephen P; Antrobus, Robin; Frezza, Christian; Nathan, James A

Bailey, Peter S J; Ortmann, Brian M; Martinelli, Anthony W; Houghton, Jack W; Costa, Ana S H; Burr, Stephen P; Antrobus, Robin; Frezza, Christian; Nathan, James A.

Afiliación

Bailey PSJ; Cambridge Institute for Medical Research, Department of Medicine, University of Cambridge, Cambridge, CB2 0XY, UK.
Ortmann BM; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, CB2 0AW, UK.
Martinelli AW; Cambridge Institute for Medical Research, Department of Medicine, University of Cambridge, Cambridge, CB2 0XY, UK.
Houghton JW; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, CB2 0AW, UK.
Costa ASH; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, CB2 0AW, UK.
Burr SP; Cambridge Institute for Medical Research, Department of Medicine, University of Cambridge, Cambridge, CB2 0XY, UK.
Antrobus R; MRC Cancer Unit, University of Cambridge, Cambridge, CB2 0XZ, UK.
Frezza C; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.
Nathan JA; Cambridge Institute for Medical Research, Department of Medicine, University of Cambridge, Cambridge, CB2 0XY, UK.

Nat Commun ; 11(1): 4046, 2020 08 13.

Article en En | MEDLINE | ID: mdl-32792488

Asunto(s)

Complejo Cetoglutarato Deshidrogenasa/metabolismo; Ácidos Cetoglutáricos/metabolismo; Mitocondrias/metabolismo; Mutagénesis/fisiología; Serina Proteasas/metabolismo; Metabolismo Energético/genética; Metabolismo Energético/fisiología; Células HeLa; Humanos; Complejo Cetoglutarato Deshidrogenasa/genética; Modelos Biológicos; Mutagénesis/genética; Serina Proteasas/genética

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Mutagénesis / Serina Proteasas / Complejo Cetoglutarato Deshidrogenasa / Ácidos Cetoglutáricos / Mitocondrias Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido

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