Cutaneous angiomas in POEMS syndrome. An ultrastructural and immunohistochemical study.
Arch Dermatol
; 124(5): 695-8, 1988 May.
Article
en En
| MEDLINE
| ID: mdl-3284467
ABSTRACT
Cutaneous manifestations of POEMS (polyneuropathy, organomegaly, endocrinopathies, M-protein, and skin changes) syndrome in a 51-year-old white man included two types of hemangiomas, ie, cherry-type and subcutaneous hemangiomas. By light microscopy and immunohistochemistry, both types of tumors showed features of capillary hemangiomas. By electron microscopy, a peculiar finding of subcutaneous hemangiomas was the presence of slender abluminal processes of endothelial cells that were frequently anastomosing to form electron-lucent blebs. Although the precise etiopathogenesis of the vascular proliferations remains speculative, these lesions merit study since they constitute an easily recognizable marker of POEMS syndrome.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Paraproteinemias
/
Neoplasias Cutáneas
/
Hemangioma
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Arch Dermatol
Año:
1988
Tipo del documento:
Article
País de afiliación:
Francia