Design and synthesis of efficient heavy-atom-free photosensitizers for photodynamic therapy of cancer.
Chem Commun (Camb)
; 56(77): 11489-11492, 2020 Sep 29.
Article
en En
| MEDLINE
| ID: mdl-32857074
ABSTRACT
Novel thiocarbonyl derivatives (NIS and CRNS) with excellent ROS generation abilities are synthesized and studied as potential photosensitizers for one- and two-photon excited photodynamic therapy. In particular, NIS-Me and CRNS display outstanding phototoxicity toward HeLa cells under two-photon excitation (800 nm) with negligible dark toxicity.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Fotoquimioterapia
/
Compuestos de Sulfhidrilo
/
Diseño de Fármacos
/
Fármacos Fotosensibilizantes
/
Antineoplásicos
Límite:
Humans
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Vietnam