Clinical implications of C6 complement component deficiency.
Allergy Asthma Proc
; 41(5): 386-388, 2020 09 01.
Article
en En
| MEDLINE
| ID: mdl-32867893
ABSTRACT
Background:
Terminal complement component deficiencies are risk factors for neisserial infections.Objective:
To review the clinical characteristics, the diagnosis and the management of patients with a terminal complement component deficiency.Methods:
Pertinent articles were selected and reviewed in relation to a case presentation of C6 deficiency.Results:
A case of a 56-year old patient with a history of meningitis, chronic rash, and C6 deficiency was presented, followed by discussion of clinical characteristics, diagnosis, and management of terminal complement component deficiencies. Clinical pearls and pitfalls were reviewed for the practicing allergist/immunologist and fellow-in-training.Conclusion:
C6 deficiency is the most common terminal complement component deficiency and can present later in age with N. meningitidis infections. Patients can be screened for terminal complement component deficiency by checking CH50.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Envejecimiento
/
Complemento C6
/
Vacunas Meningococicas
/
Enfermedades por Deficiencia de Complemento Hereditario
/
Meningitis Meningocócica
/
Neisseria meningitidis
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Allergy Asthma Proc
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
2020
Tipo del documento:
Article