Successful cord blood transplantation for myelodysplastic syndrome complicated by Mycobacterium kansasii pneumonia.
Transpl Infect Dis
; 23(4): e13463, 2021 Aug.
Article
en En
| MEDLINE
| ID: mdl-32918515
ABSTRACT
Non-tuberculous mycobacterial (NTM) disease is a rare cause of neutropenic fever in patients with hematological malignancies. There are few studies on the optimal management for such patients with NTM. We report a case of myelodysplastic syndrome (MDS) treated by umbilical cord blood transplantation (CBT) after Mycobacterium kansasii (M kansasii) pneumonia. A 38-year-old man diagnosed with MDS developed severe pneumonia during induction chemotherapy. Repeated sputum culture uncovered mycobacterium infection. Then, by the polymerase chain reaction of the bronchial lavage fluid, M kansasii infection was proven. After 140 days of anti-NTM therapy, CBT was successfully carried out and the patient recovered without recurrence of NTM infection. This case provides valuable evidence that hematopoietic stem cell transplantation is feasible after a reliable diagnosis and continuous anti-NTM therapy.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neumonía
/
Síndromes Mielodisplásicos
/
Trasplante de Células Madre Hematopoyéticas
/
Mycobacterium kansasii
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Trasplante de Células Madre de Sangre del Cordón Umbilical
/
Infecciones por Mycobacterium no Tuberculosas
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Transpl Infect Dis
Asunto de la revista:
TRANSPLANTE
Año:
2021
Tipo del documento:
Article
País de afiliación:
Japón