Cytotoxic Xanthone Derivatives from the Mangrove-Derived Endophytic Fungus Peniophora incarnata Z4.
J Nat Prod
; 83(10): 2976-2982, 2020 10 23.
Article
en En
| MEDLINE
| ID: mdl-32975117
ABSTRACT
The mangrove-derived endophytic fungus Peniophora incarnata Z4 produced seven new xanthone derivatives, including four new tetrahydroxanthones (1-4), one new chromone (5), one new xanthone (6), and one new xanthone dimer (7), together with one known compound, globosuxanthone B (8). Their structures were determined by an extensive analysis of 1D and 2D NMR, HRESIMS, ECD, and single-crystal X-ray diffraction data. In cytotoxic activity assays, compound 2 showed cytotoxicity against three carcinoma cell lines with IC50 values less than 10 µM.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Basidiomycota
/
Estructura Molecular
/
Xantonas
Idioma:
En
Revista:
J Nat Prod
Año:
2020
Tipo del documento:
Article
País de afiliación:
China