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STAT3 deficiency in B cells exacerbates uveitis by promoting expansion of pathogenic lymphocytes and suppressing regulatory B cells (Bregs) and Tregs.
Oladipupo, Favour O; Yu, Cheng-Rong; Olumuyide, Ezekiel; Jittaysothorn, Yingyos; Choi, Jin Kyeong; Egwuagu, Charles E.
Afiliación
  • Oladipupo FO; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Building 10, Room 10N248G, 10 Center Drive, Bethesda, MD, 20892-1857, USA.
  • Yu CR; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Building 10, Room 10N248G, 10 Center Drive, Bethesda, MD, 20892-1857, USA.
  • Olumuyide E; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Building 10, Room 10N248G, 10 Center Drive, Bethesda, MD, 20892-1857, USA.
  • Jittaysothorn Y; Immunoregulation Section, Laboratory of Immunology, NEI, NIH, Bethesda, MD, USA.
  • Choi JK; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Building 10, Room 10N248G, 10 Center Drive, Bethesda, MD, 20892-1857, USA.
  • Egwuagu CE; Department of Immunology, Jeonbuk National University Medical School, Jeonju, Jeonbuk, 54896, Republic of Korea.
Sci Rep ; 10(1): 16188, 2020 10 01.
Article en En | MEDLINE | ID: mdl-33004854
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Uveítis / Linfocitos T Reguladores / Células TH1 / Factor de Transcripción STAT3 / Células Th17 / Linfocitos B Reguladores Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Uveítis / Linfocitos T Reguladores / Células TH1 / Factor de Transcripción STAT3 / Células Th17 / Linfocitos B Reguladores Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos