Clinical evaluation of an application aid for less-invasive surfactant administration (LISA).
Arch Dis Child Fetal Neonatal Ed
; 106(2): 211-214, 2021 Mar.
Article
en En
| MEDLINE
| ID: mdl-33023914
ABSTRACT
BACKGROUND:
Less-invasive surfactant administration (LISA) is increasingly used. We investigated the feasibility of a new LISA-device (Neofact®) in neonates.DESIGN:
Prospective observational pilot study with open-label LISA in two tertiary neonatal intensive care units. PATIENTS 20 infants with a gestational age of ≥26+0/7 weeks and an indication for LISA (Respiratory Severity Score (RSS)≥5 or fraction of inspired oxygen (FiO2) ≥0.30). Infants with respiratory tract malformations or unavailability of an instructed neonatologist were excluded. MAIN OUTCOMEMEASURES:
Success of LISA, defined as laryngoscopy-confirmed intratracheal catheter position or a decrease in FiO2 by ≥0.05 or to 0.21, accompanied by an RSS decrease of ≥2; number of attempts needed for tracheal catheterisation.RESULTS:
20/57 screened infants were enrolled. Successful application occurred in 19/20 (95%). One application failed after three attempts. No device-related adverse events occurred. The median number of attempts was 2, success rate per attempt 19/31 (61%).CONCLUSION:
LISA via Neofact® appears feasible.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Síndrome de Dificultad Respiratoria del Recién Nacido
/
Surfactantes Pulmonares
Tipo de estudio:
Observational_studies
Límite:
Humans
/
Newborn
Idioma:
En
Revista:
Arch Dis Child Fetal Neonatal Ed
Asunto de la revista:
PEDIATRIA
/
PERINATOLOGIA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Alemania