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Selective Tumor Cell Apoptosis and Tumor Regression in CDH17-Positive Colorectal Cancer Models using BI 905711, a Novel Liver-Sparing TRAILR2 Agonist.
García-Martínez, Juan Manuel; Wang, Shirley; Weishaeupl, Cordula; Wernitznig, Andreas; Chetta, Paolo; Pinto, Catarina; Ho, Jason; Dutcher, Darrin; Gorman, Philip N; Kroe-Barrett, Rachel; Rinnenthal, Joerg; Giragossian, Craig; Impagnatiello, Maria Antonietta; Tirapu, Iñigo; Hilberg, Frank; Kraut, Norbert; Pearson, Mark; Kuenkele, Klaus Peter.
Afiliación
  • García-Martínez JM; Boehringer Ingelheim Cancer Research Therapeutic Area, Vienna, Austria. juan_manuel.garcia-martinez@boehringer-ingelheim.com.
  • Wang S; Boehringer Ingelheim Cancer Research Therapeutic Area, Vienna, Austria.
  • Weishaeupl C; Boehringer Ingelheim Cancer Research Therapeutic Area, Vienna, Austria.
  • Wernitznig A; Boehringer Ingelheim Cancer Research Therapeutic Area, Vienna, Austria.
  • Chetta P; Boehringer Ingelheim Cancer Research Therapeutic Area, Vienna, Austria.
  • Pinto C; Boehringer Ingelheim Cancer Immunology and Immune Modulation, Vienna, Austria.
  • Ho J; Boehringer Ingelheim Biotherapeutics Discovery Research, Ridgefield, Connecticut.
  • Dutcher D; Boehringer Ingelheim Biotherapeutics Discovery Research, Ridgefield, Connecticut.
  • Gorman PN; Boehringer Ingelheim Biotherapeutics Discovery Research, Ridgefield, Connecticut.
  • Kroe-Barrett R; Boehringer Ingelheim Biotherapeutics Discovery Research, Ridgefield, Connecticut.
  • Rinnenthal J; Boehringer Ingelheim Cancer Research Therapeutic Area, Vienna, Austria.
  • Giragossian C; Boehringer Ingelheim Biotherapeutics Discovery Research, Ridgefield, Connecticut.
  • Impagnatiello MA; Boehringer Ingelheim Cancer Research Therapeutic Area, Vienna, Austria.
  • Tirapu I; Boehringer Ingelheim Cancer Immunology and Immune Modulation, Vienna, Austria.
  • Hilberg F; Boehringer Ingelheim Cancer Research Therapeutic Area, Vienna, Austria.
  • Kraut N; Boehringer Ingelheim Cancer Research Therapeutic Area, Vienna, Austria.
  • Pearson M; Boehringer Ingelheim Cancer Research Therapeutic Area, Vienna, Austria.
  • Kuenkele KP; Boehringer Ingelheim Cancer Research Therapeutic Area, Vienna, Austria.
Mol Cancer Ther ; 20(1): 96-108, 2021 01.
Article en En | MEDLINE | ID: mdl-33037135
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Cadherinas / Apoptosis / Anticuerpos Biespecíficos / Ensayos Antitumor por Modelo de Xenoinjerto / Receptores del Ligando Inductor de Apoptosis Relacionado con TNF / Hígado Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2021 Tipo del documento: Article País de afiliación: Austria
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Cadherinas / Apoptosis / Anticuerpos Biespecíficos / Ensayos Antitumor por Modelo de Xenoinjerto / Receptores del Ligando Inductor de Apoptosis Relacionado con TNF / Hígado Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2021 Tipo del documento: Article País de afiliación: Austria