DeepC: predicting 3D genome folding using megabase-scale transfer learning.

Schwessinger, Ron; Gosden, Matthew; Downes, Damien; Brown, Richard C; Oudelaar, A Marieke; Telenius, Jelena; Teh, Yee Whye; Lunter, Gerton; Hughes, Jim R

Schwessinger, Ron; Gosden, Matthew; Downes, Damien; Brown, Richard C; Oudelaar, A Marieke; Telenius, Jelena; Teh, Yee Whye; Lunter, Gerton; Hughes, Jim R.

Afiliación

Schwessinger R; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Gosden M; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Downes D; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Brown RC; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Oudelaar AM; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Telenius J; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
Teh YW; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Lunter G; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Hughes JR; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

Nat Methods ; 17(11): 1118-1124, 2020 11.

Article en En | MEDLINE | ID: mdl-33046896

Asunto(s)

Genoma Humano/genética; Genómica/métodos; Modelos Genéticos; Redes Neurales de la Computación; Secuencia de Bases; Factor de Unión a CCCTC/genética; Cromatina/genética; Simulación por Computador; Variación Estructural del Genoma; Humanos

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Genoma Humano / Redes Neurales de la Computación / Genómica / Modelos Genéticos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nat Methods Asunto de la revista: TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido

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