miR-146a-5p improves the decidual cytokine microenvironment by regulating the toll-like receptor signaling pathway in unexplained spontaneous abortion.

Ye, Hong-Xia; Li, Lan; Dong, Ya-Jun; Li, Peng-Hao; Su, Qin; Guo, Yan-Hua; Lu, Yan-Rong; Zhong, Ying; Jia, Yan; Cheng, Jing-Qiu

Ye, Hong-Xia; Li, Lan; Dong, Ya-Jun; Li, Peng-Hao; Su, Qin; Guo, Yan-Hua; Lu, Yan-Rong; Zhong, Ying; Jia, Yan; Cheng, Jing-Qiu.

Afiliación

Ye HX; Key Laboratory of Transplant Engineering and Immunology and National Clinical Research Centre for Geriatrics, West China Hospital, Sichuan University, No 37 Guoxue Road, Chengdu 610041, Sichuan, China; Department of Reproductive Immunology, Chengdu Xi'nan Gynecology Hospital, No 66 and 88 Bisheng Ro
Li L; Key Laboratory of Transplant Engineering and Immunology and National Clinical Research Centre for Geriatrics, West China Hospital, Sichuan University, No 37 Guoxue Road, Chengdu 610041, Sichuan, China.
Dong YJ; Department of Reproductive Immunology, Chengdu Xi'nan Gynecology Hospital, No 66 and 88 Bisheng Road, Chengdu 610066, Sichuan, China.
Li PH; Jinxin Research Institute for Reproductive Medicine and Genetics, Chengdu Xi'nan Gynecology Hospital Co., Ltd., No 66 and 88 Bisheng Road, Chengdu 610066, Sichuan, China.
Su Q; Department of Reproductive Immunology, Chengdu Xi'nan Gynecology Hospital, No 66 and 88 Bisheng Road, Chengdu 610066, Sichuan, China.
Guo YH; Department of Reproductive Immunology, Chengdu Xi'nan Gynecology Hospital, No 66 and 88 Bisheng Road, Chengdu 610066, Sichuan, China.
Lu YR; Key Laboratory of Transplant Engineering and Immunology and National Clinical Research Centre for Geriatrics, West China Hospital, Sichuan University, No 37 Guoxue Road, Chengdu 610041, Sichuan, China.
Zhong Y; Department of Reproductive Immunology, Chengdu Xi'nan Gynecology Hospital, No 66 and 88 Bisheng Road, Chengdu 610066, Sichuan, China.
Jia Y; Department of Reproductive Immunology, Chengdu Xi'nan Gynecology Hospital, No 66 and 88 Bisheng Road, Chengdu 610066, Sichuan, China. Electronic address: jiay@jxr-fertility.com.
Cheng JQ; Key Laboratory of Transplant Engineering and Immunology and National Clinical Research Centre for Geriatrics, West China Hospital, Sichuan University, No 37 Guoxue Road, Chengdu 610041, Sichuan, China. Electronic address: jqcheng@scu.edu.cn.

Int Immunopharmacol ; 89(Pt B): 107066, 2020 Dec.

Article en En | MEDLINE | ID: mdl-33059199

Asunto(s)

Aborto Espontáneo/metabolismo; Citocinas/metabolismo; Decidua/metabolismo; Mediadores de Inflamación/metabolismo; MicroARNs/metabolismo; Receptores Toll-Like/metabolismo; Aborto Espontáneo/genética; Aborto Espontáneo/inmunología; Adulto; Estudios de Casos y Controles; Células Cultivadas; Microambiente Celular; Citocinas/genética; Decidua/inmunología; Femenino; Regulación de la Expresión Génica; Redes Reguladoras de Genes; Humanos; MicroARNs/genética; Embarazo; Mapas de Interacción de Proteínas; Transducción de Señal; Receptores Toll-Like/genética

Palabras clave

Bioinformatics; Decidual cytokine microenvironment; Toll-like signaling pathway; Unexplained spontaneous abortion; microRNA-146a-5p

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Aborto Espontáneo / Citocinas / Mediadores de Inflamación / Decidua / MicroARNs / Receptores Toll-Like Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2020 Tipo del documento: Article

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