Intact and subunit-specific analysis of bispecific antibodies by sheathless CE-MS.

Gstöttner, Christoph; Nicolardi, Simone; Haberger, Markus; Reusch, Dietmar; Wuhrer, Manfred; Domínguez-Vega, Elena

Gstöttner, Christoph; Nicolardi, Simone; Haberger, Markus; Reusch, Dietmar; Wuhrer, Manfred; Domínguez-Vega, Elena.

Afiliación

Gstöttner C; Leiden University Medical Center, Center for Proteomics and Metabolomics, the Netherlands.
Nicolardi S; Leiden University Medical Center, Center for Proteomics and Metabolomics, the Netherlands.
Haberger M; Pharma Technical Development Penzberg, Roche Diagnostics GmbH, Penzberg, Germany.
Reusch D; Pharma Technical Development Penzberg, Roche Diagnostics GmbH, Penzberg, Germany.
Wuhrer M; Leiden University Medical Center, Center for Proteomics and Metabolomics, the Netherlands.
Domínguez-Vega E; Leiden University Medical Center, Center for Proteomics and Metabolomics, the Netherlands. Electronic address: e.dominguez_vega@lumc.nl.

Anal Chim Acta ; 1134: 18-27, 2020 Oct 16.

Article en En | MEDLINE | ID: mdl-33059862

Asunto(s)

Anticuerpos Biespecíficos; Electroforesis Capilar; Glicosilación; Espectrometría de Masas; Procesamiento Proteico-Postraduccional

Palabras clave

Bispecific monoclonal antibodies; Intact protein analysis; Mass spectrometry; Middle-up analysis; Sheathless capillary electrophoresis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Anticuerpos Biespecíficos Idioma: En Revista: Anal Chim Acta Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos

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