Insights into Fasciola hepatica Juveniles: Crossing the Fasciolosis Rubicon.
Trends Parasitol
; 37(1): 35-47, 2021 01.
Article
en En
| MEDLINE
| ID: mdl-33067132
ABSTRACT
Unraveling the molecular interactions governing the first contact between parasite and host tissues is of paramount importance to the development of effective control strategies against parasites. In fasciolosis, a foodborne trematodiasis caused mainly by Fasciola hepatica, these early interactions occur between the juvenile worm and the host intestinal wall a few hours after ingestion of metacercariae, the infectious stage of the parasite. However, research on these early events is still scarce and the majority of studies have focused on the adult worm. Here, we review current knowledge on the biology and biochemistry of F. hepatica juveniles and their molecular relationships with the host tissues and identify the research needs and gaps to be covered in the future.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Fascioliasis
/
Interacciones Huésped-Parásitos
Límite:
Animals
Idioma:
En
Revista:
Trends Parasitol
Asunto de la revista:
PARASITOLOGIA
Año:
2021
Tipo del documento:
Article