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Overcoming T-cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH.
Sengal, Amel; Velazquez, Jessica; Hahne, Meryl; Burke, Thomas M; Abhyankar, Harshal; Reyes, Robert; Olea, Walter; Scull, Brooks; Eckstein, Olive S; Bigenwald, Camille; Bollard, Catherine M; Yu, Wendong; Merad, Miriam; McClain, Kenneth L; Allen, Carl E; Chakraborty, Rikhia.
Afiliación
  • Sengal A; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX.
  • Velazquez J; Division of Pediatric Hematology-Oncology, Department of Pediatrics and.
  • Hahne M; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX.
  • Burke TM; Division of Pediatric Hematology-Oncology, Department of Pediatrics and.
  • Abhyankar H; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX.
  • Reyes R; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX.
  • Olea W; Division of Pediatric Hematology-Oncology, Department of Pediatrics and.
  • Scull B; Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX.
  • Eckstein OS; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX.
  • Bigenwald C; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX.
  • Bollard CM; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX.
  • Yu W; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX.
  • Merad M; Texas Children's Cancer Center, Texas Children's Hospital, Houston, TX.
  • McClain KL; Department of Oncological Sciences, Tisch Cancer Institute, and.
  • Allen CE; Department of Dermatology, Icahn School of Medicine, New York, NY.
  • Chakraborty R; Center for Cancer and Immunology Research, Children's National Medical Center, Washington, DC.
Blood ; 137(13): 1777-1791, 2021 04 01.
Article en En | MEDLINE | ID: mdl-33075814
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos / Histiocitosis de Células de Langerhans / Linfocitos T CD8-positivos / Inhibidores de Proteínas Quinasas / Inhibidores de Puntos de Control Inmunológico Límite: Animals / Humans Idioma: En Revista: Blood Año: 2021 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos / Histiocitosis de Células de Langerhans / Linfocitos T CD8-positivos / Inhibidores de Proteínas Quinasas / Inhibidores de Puntos de Control Inmunológico Límite: Animals / Humans Idioma: En Revista: Blood Año: 2021 Tipo del documento: Article