Fecal microbiota transplantation in the intestinal decolonization of carbapenamase-producing enterobacteriaceae.
Rev Esp Enferm Dig
; 112(12): 925-928, 2020 Dec.
Article
en En
| MEDLINE
| ID: mdl-33118360
ABSTRACT
BACKGROUND AND AIMS:
fecal microbiota transplantation (FMT) is effective for recurrent Clostridium difficile infection (CDI). Intestinal decolonization of carbapenamase-producing enterobacteriaceae (CPE) can prevent transmission and infection by these agents. The aim of this study was to assess CPE decolonization after FMT.METHODS:
this was a case-series study that consecutively included all CPE-carriers that underwent FMT between 2014 and 2019. The indications included refractory/recurrent CDI and CPE-decolonization.RESULTS:
out of 21 CPE-carriers, eight were excluded due to incomplete post-FMT testing. CPE decolonization was confirmed in 76.9 % (n = 10). The median decolonization time was 16-weeks (IQR-23) and ranged from two to 53 weeks.CONCLUSION:
FMT may be used in the clinical practice for CPE-decolonization as an alternative to combined antibiotic regimens.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Infecciones por Clostridium
/
Trasplante de Microbiota Fecal
Límite:
Humans
Idioma:
En
Revista:
Rev Esp Enferm Dig
Asunto de la revista:
GASTROENTEROLOGIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Portugal