Prenylated xanthones and benzophenones from the fruits of Garcinia bracteata and their potential antiproliferative and anti-inflammatory activities.

Xue, Qing; Chen, Yu; Yin, Huijun; Teng, Haida; Qin, Rui; Liu, Hong; Li, Qingqing; Mei, Zhinan; Yang, Guangzhong

Xue, Qing; Chen, Yu; Yin, Huijun; Teng, Haida; Qin, Rui; Liu, Hong; Li, Qingqing; Mei, Zhinan; Yang, Guangzhong.

Afiliación

Xue Q; School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, PR China; College of Life Sciences, South-Central University for Nationalities, Wuhan 430074, PR China.
Chen Y; College of Chemistry and Material Sciences, South-Central University for Nationalities, Wuhan 430074, PR China.
Yin H; College of Life Sciences, South-Central University for Nationalities, Wuhan 430074, PR China.
Teng H; College of Chemistry and Material Sciences, South-Central University for Nationalities, Wuhan 430074, PR China.
Qin R; College of Life Sciences, South-Central University for Nationalities, Wuhan 430074, PR China.
Liu H; College of Life Sciences, South-Central University for Nationalities, Wuhan 430074, PR China.
Li Q; School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, PR China.
Mei Z; School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, PR China. Electronic address: meizhinan@163.com.
Yang G; School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, PR China. Electronic address: yanggz888@126.com.

Bioorg Chem ; 104: 104339, 2020 11.

Article en En | MEDLINE | ID: mdl-33142411

Asunto(s)

Antiinflamatorios/farmacología; Antineoplásicos Fitogénicos/farmacología; Benzofenonas/farmacología; Frutas/química; Garcinia/química; Óxido Nítrico/antagonistas & inhibidores; Xantonas/farmacología; Animales; Antiinflamatorios/química; Antiinflamatorios/aislamiento & purificación; Antineoplásicos Fitogénicos/química; Antineoplásicos Fitogénicos/aislamiento & purificación; Benzofenonas/química; Benzofenonas/aislamiento & purificación; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Supervivencia Celular/efectos de los fármacos; Cristalografía por Rayos X; Relación Dosis-Respuesta a Droga; Ensayos de Selección de Medicamentos Antitumorales; Humanos; Lipopolisacáridos/antagonistas & inhibidores; Lipopolisacáridos/farmacología; Ratones; Modelos Moleculares; Estructura Molecular; Óxido Nítrico/biosíntesis; Células RAW 264.7; Relación Estructura-Actividad; Xantonas/química; Xantonas/aislamiento & purificación

Palabras clave

Anti-inflammatory activity; Antiproliferative activity; Garcinia bracteata; Prenylated xanthones; Rearranged benzophenones

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Benzofenonas / Garcinia / Xantonas / Frutas / Antiinflamatorios / Óxido Nítrico / Antineoplásicos Fitogénicos Límite: Animals / Humans Idioma: En Revista: Bioorg Chem Año: 2020 Tipo del documento: Article

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