High proportion of anergic B cells in the bone marrow defined phenotypically by CD21(-/low)/CD38- expression predicts poor survival in diffuse large B cell lymphoma.

Rijal, Sewa; Kok, Johanna; Coombes, Caitlin; Smyth, Lillian; Hourigan, Jayde; Jain, Sanjiv; Talaulikar, Dipti

Rijal, Sewa; Kok, Johanna; Coombes, Caitlin; Smyth, Lillian; Hourigan, Jayde; Jain, Sanjiv; Talaulikar, Dipti.

Afiliación

Rijal S; Australian National University Medical School, College of Medicine, Biology and Environment, Canberra, Australia.
Kok J; Haematology Translational Research Unit, Department of Hematology, Canberra Hospital, Canberra, Australia.
Coombes C; Haematology Translational Research Unit, Department of Hematology, Canberra Hospital, Canberra, Australia.
Smyth L; Australian National University Medical School, College of Medicine, Biology and Environment, Canberra, Australia.
Hourigan J; Haematology Translational Research Unit, Department of Hematology, Canberra Hospital, Canberra, Australia.
Jain S; Australian National University Medical School, College of Medicine, Biology and Environment, Canberra, Australia.
Talaulikar D; Department of Diagnostic Genomics, Canberra Hospital, Canberra, Australia.

BMC Cancer ; 20(1): 1061, 2020 Nov 03.

Article en En | MEDLINE | ID: mdl-33143694

Asunto(s)

ADP-Ribosil Ciclasa 1/metabolismo; Linfocitos B/inmunología; Médula Ósea/inmunología; Linfoma de Células B Grandes Difuso/mortalidad; Glicoproteínas de Membrana/metabolismo; Receptores de Complemento 3d/metabolismo; Adulto; Anciano; Anciano de 80 o más Años; Anergia Clonal; Regulación hacia Abajo; Femenino; Citometría de Flujo; Humanos; Linfoma de Células B Grandes Difuso/inmunología; Masculino; Persona de Mediana Edad; Pronóstico; Análisis de Regresión; Análisis de Supervivencia

Palabras clave

Anergic; B cells; Diffuse large B cell lymphoma; Microenvironment; Prognosis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Médula Ósea / Glicoproteínas de Membrana / Linfocitos B / Linfoma de Células B Grandes Difuso / Receptores de Complemento 3d / ADP-Ribosil Ciclasa 1 Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: BMC Cancer Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Australia

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