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GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates.
Breen, Danna M; Kim, Hanna; Bennett, Donald; Calle, Roberto A; Collins, Susie; Esquejo, Ryan M; He, Tao; Joaquim, Stephanie; Joyce, Alison; Lambert, Matthew; Lin, Laura; Pettersen, Betty; Qiao, Shuxi; Rossulek, Michelle; Weber, Gregory; Wu, Zhidan; Zhang, Bei B; Birnbaum, Morris J.
Afiliación
  • Breen DM; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA. Electronic address: danna.breen@pfizer.com.
  • Kim H; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Bennett D; Biostatistics, Early Clinical Development, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Calle RA; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Collins S; Biostatistics, Early Clinical Development, Pfizer R&D UK Limited, Ramsgate Road, Sandwich, Kent, UK.
  • Esquejo RM; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • He T; Biomedicine Design, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Joaquim S; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Joyce A; Biomedicine Design, Pfizer Inc., 1 Burtt Road, Andover, MA, USA.
  • Lambert M; Biomedicine Design, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Lin L; Biomedicine Design, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Pettersen B; Drug Safety Research and Development, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Qiao S; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Rossulek M; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Weber G; Biomedicine Design, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Wu Z; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Zhang BB; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Birnbaum MJ; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
Cell Metab ; 32(6): 938-950.e6, 2020 12 01.
Article en En | MEDLINE | ID: mdl-33207247
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Platino (Metal) / Vómitos / Anorexia / Factor 15 de Diferenciación de Crecimiento / Neoplasias / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Platino (Metal) / Vómitos / Anorexia / Factor 15 de Diferenciación de Crecimiento / Neoplasias / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2020 Tipo del documento: Article