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Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities.
Mehtonen, Juha; Teppo, Susanna; Lahnalampi, Mari; Kokko, Aleksi; Kaukonen, Riina; Oksa, Laura; Bouvy-Liivrand, Maria; Malyukova, Alena; Mäkinen, Artturi; Laukkanen, Saara; Mäkinen, Petri I; Rounioja, Samuli; Ruusuvuori, Pekka; Sangfelt, Olle; Lund, Riikka; Lönnberg, Tapio; Lohi, Olli; Heinäniemi, Merja.
Afiliación
  • Mehtonen J; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Yliopistonranta 1, FI-70211, Kuopio, Finland.
  • Teppo S; BioMediTech, Faculty of Medicine and Health Technology, Tampere University, FI-33014, Tampere, Finland.
  • Lahnalampi M; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Yliopistonranta 1, FI-70211, Kuopio, Finland.
  • Kokko A; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Yliopistonranta 1, FI-70211, Kuopio, Finland.
  • Kaukonen R; Turku Bioscience Centre, University of Turku and Åbo Akademi University, FI-20520, Turku, Finland.
  • Oksa L; BioMediTech, Faculty of Medicine and Health Technology, Tampere University, FI-33014, Tampere, Finland.
  • Bouvy-Liivrand M; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Yliopistonranta 1, FI-70211, Kuopio, Finland.
  • Malyukova A; Department of Cell and Molecular Biology, Karolinska Institutet, SE-171 77, Stockholm, Sweden.
  • Mäkinen A; BioMediTech, Faculty of Medicine and Health Technology, Tampere University, FI-33014, Tampere, Finland.
  • Laukkanen S; BioMediTech, Faculty of Medicine and Health Technology, Tampere University, FI-33014, Tampere, Finland.
  • Mäkinen PI; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Yliopistonranta 1, FI-70211, Kuopio, Finland.
  • Rounioja S; Fimlab Laboratories, FI-33520, Tampere, Finland.
  • Ruusuvuori P; BioMediTech, Faculty of Medicine and Health Technology, Tampere University, FI-33014, Tampere, Finland.
  • Sangfelt O; Department of Cell and Molecular Biology, Karolinska Institutet, SE-171 77, Stockholm, Sweden.
  • Lund R; Turku Bioscience Centre, University of Turku and Åbo Akademi University, FI-20520, Turku, Finland.
  • Lönnberg T; Turku Bioscience Centre, University of Turku and Åbo Akademi University, FI-20520, Turku, Finland.
  • Lohi O; BioMediTech, Faculty of Medicine and Health Technology, Tampere University, FI-33014, Tampere, Finland.
  • Heinäniemi M; Tays Cancer Centre, Tampere University Hospital, Tampere, Finland.
Genome Med ; 12(1): 99, 2020 11 20.
Article en En | MEDLINE | ID: mdl-33218352
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Linfocitos / Leucemia / Diferenciación Celular / Proliferación Celular / Proteínas Proto-Oncogénicas c-ets / Subunidad alfa 2 del Factor de Unión al Sitio Principal Tipo de estudio: Prognostic_studies Límite: Child / Humans Idioma: En Revista: Genome Med Año: 2020 Tipo del documento: Article País de afiliación: Finlandia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Linfocitos / Leucemia / Diferenciación Celular / Proliferación Celular / Proteínas Proto-Oncogénicas c-ets / Subunidad alfa 2 del Factor de Unión al Sitio Principal Tipo de estudio: Prognostic_studies Límite: Child / Humans Idioma: En Revista: Genome Med Año: 2020 Tipo del documento: Article País de afiliación: Finlandia