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Collagen release by human hepatic stellate cells requires vitamin C and is efficiently blocked by hydroxylase inhibition.
Smith-Cortinez, Natalia; Fagundes, Raphael R; Gomez, Valentina; Kong, Defu; de Waart, Dirk R; Heegsma, Janette; Sydor, Svenja; Olinga, Peter; de Meijer, Vincent E; Taylor, Cormac T; Bank, Ruud; Paulusma, Coen C; Faber, Klaas Nico.
Afiliación
  • Smith-Cortinez N; Department of Hepatology and Gastroenterology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Fagundes RR; Department of Hepatology and Gastroenterology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Gomez V; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Kong D; Department of Hepatology and Gastroenterology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • de Waart DR; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Heegsma J; Department of Hepatology and Gastroenterology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Sydor S; Department of Internal Medicine, University Hospital Knappschaftskrankenhaus, Ruhr-University Bochum, Bochum, Germany.
  • Olinga P; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Groningen, the Netherlands.
  • de Meijer VE; Department of Surgery, Division of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Taylor CT; School of Medicine and Medical Science and the Conway Institute, University College Dublin, Dublin, Ireland.
  • Bank R; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Paulusma CC; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Faber KN; Department of Hepatology and Gastroenterology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
FASEB J ; 35(2): e21219, 2021 02.
Article en En | MEDLINE | ID: mdl-33236467
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácido Ascórbico / Colágeno Tipo I / Células Estrelladas Hepáticas / Inhibidores de Prolil-Hidroxilasa / Aminoácidos Dicarboxílicos / Cirrosis Hepática Límite: Animals / Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácido Ascórbico / Colágeno Tipo I / Células Estrelladas Hepáticas / Inhibidores de Prolil-Hidroxilasa / Aminoácidos Dicarboxílicos / Cirrosis Hepática Límite: Animals / Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos