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Inhibition of Acetyl-CoA Carboxylase Causes Malformations in Rats and Rabbits: Comparison of Mammalian Findings and Alternative Assays.
Catlin, Natasha R; Bowman, Christopher J; Campion, Sarah N; Davenport, Scott D; Esler, William P; Kumpf, Steven W; Lewis, Elise M; Nowland, William S; Ross, Trenton T; Stedman, Donald S; Stethem, Christine; Cappon, Gregg D.
Afiliación
  • Catlin NR; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT.
  • Bowman CJ; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT.
  • Campion SN; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT.
  • Davenport SD; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT.
  • Esler WP; Internal Medicine Research Unit, Pfizer Worldwide Research & Development, Cambridge, MA.
  • Kumpf SW; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT.
  • Lewis EM; Charles River Laboratories, Inc, Safety Assessment, Horsham, PA.
  • Nowland WS; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT.
  • Ross TT; Internal Medicine Research Unit, Pfizer Worldwide Research & Development, Cambridge, MA.
  • Stedman DS; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT.
  • Stethem C; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT.
  • Cappon GD; Drug Safety Research and Development, Pfizer Worldwide Research & Development, Groton, CT.
Toxicol Sci ; 179(2): 183-194, 2021 01 28.
Article en En | MEDLINE | ID: mdl-33247737
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Acetil-CoA Carboxilasa / Diabetes Mellitus Tipo 2 Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Toxicol Sci Asunto de la revista: TOXICOLOGIA Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Acetil-CoA Carboxilasa / Diabetes Mellitus Tipo 2 Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Toxicol Sci Asunto de la revista: TOXICOLOGIA Año: 2021 Tipo del documento: Article