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High-resolution X-ray structure of three microtubule-stabilizing agents in complex with tubulin provide a rationale for drug design.
Xiao, Qingjie; Xue, Ting; Shuai, Wen; Wu, Chengyong; Zhang, Zhixiong; Zhang, Ting; Zeng, Shaoxue; Sun, Bo; Wang, Yuxi.
Afiliación
  • Xiao Q; Cancer Center, West China Hospital, Sichuan University, And Collaborative Innovation Center of Biotherapy, Chengdu, 610041, People's Republic of China. Electronic address: 659096188@qq.com.
  • Xue T; Precision Medicine Research Center, Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China. Electronic address: 961932935@qq.com.
  • Shuai W; Cancer Center, West China Hospital, Sichuan University, And Collaborative Innovation Center of Biotherapy, Chengdu, 610041, People's Republic of China. Electronic address: shuaiwen05@163.com.
  • Wu C; Cancer Center, West China Hospital, Sichuan University, And Collaborative Innovation Center of Biotherapy, Chengdu, 610041, People's Republic of China. Electronic address: allenwu1991@163.com.
  • Zhang Z; Cancer Center, West China Hospital, Sichuan University, And Collaborative Innovation Center of Biotherapy, Chengdu, 610041, People's Republic of China. Electronic address: zxzhang1022@163.com.
  • Zhang T; Save Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2008, Australia. Electronic address: ting.zhang@sydney.edu.au.
  • Zeng S; Save Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2008, Australia. Electronic address: shaoxue.zeng@sydney.edu.au.
  • Sun B; Shanghai Synchrotron Radiation Facility Science Center, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, 201204, People's Republic of China. Electronic address: sunbo@sinap.ac.cn.
  • Wang Y; Cancer Center, West China Hospital, Sichuan University, And Collaborative Innovation Center of Biotherapy, Chengdu, 610041, People's Republic of China; Precision Medicine Research Center, Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, 610041,
Biochem Biophys Res Commun ; 534: 330-336, 2021 01 01.
Article en En | MEDLINE | ID: mdl-33272565
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tubulina (Proteína) / Epotilonas / Moduladores de Tubulina / Microtúbulos Límite: Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tubulina (Proteína) / Epotilonas / Moduladores de Tubulina / Microtúbulos Límite: Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2021 Tipo del documento: Article