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MEK reduces cancer-specific PpIX accumulation through the RSK-ABCB1 and HIF-1α-FECH axes.
Chelakkot, Vipin Shankar; Liu, Kaiwen; Yoshioka, Ema; Saha, Shaykat; Xu, Danyang; Licursi, Maria; Dorward, Ann; Hirasawa, Kensuke.
Afiliación
  • Chelakkot VS; Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, 300 Prince Philip Drive, St. John's, NL, A1B 3V6, Canada.
  • Liu K; Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, 300 Prince Philip Drive, St. John's, NL, A1B 3V6, Canada.
  • Yoshioka E; Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, 300 Prince Philip Drive, St. John's, NL, A1B 3V6, Canada.
  • Saha S; Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, 300 Prince Philip Drive, St. John's, NL, A1B 3V6, Canada.
  • Xu D; Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, 300 Prince Philip Drive, St. John's, NL, A1B 3V6, Canada.
  • Licursi M; Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, 300 Prince Philip Drive, St. John's, NL, A1B 3V6, Canada.
  • Dorward A; Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, 300 Prince Philip Drive, St. John's, NL, A1B 3V6, Canada.
  • Hirasawa K; Division of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, 300 Prince Philip Drive, St. John's, NL, A1B 3V6, Canada. kensuke@mun.ca.
Sci Rep ; 10(1): 22124, 2020 12 17.
Article en En | MEDLINE | ID: mdl-33335181
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Protoporfirinas / Quinasas de Proteína Quinasa Activadas por Mitógenos / Proteínas Quinasas S6 Ribosómicas 90-kDa / Subunidad alfa del Factor 1 Inducible por Hipoxia / Ferroquelatasa / Neoplasias Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Protoporfirinas / Quinasas de Proteína Quinasa Activadas por Mitógenos / Proteínas Quinasas S6 Ribosómicas 90-kDa / Subunidad alfa del Factor 1 Inducible por Hipoxia / Ferroquelatasa / Neoplasias Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Canadá