Role of MDA5 in regulating CXCL10 expression induced by TLR3 signaling in human rheumatoid fibroblast-like synoviocytes.

Saruga, Tatsuro; Imaizumi, Tadaatsu; Kawaguchi, Shogo; Seya, Kazuhiko; Matsumiya, Tomoh; Sasaki, Eiji; Sasaki, Norihiro; Uesato, Ryoko; Ishibashi, Yasuyuki

Saruga, Tatsuro; Imaizumi, Tadaatsu; Kawaguchi, Shogo; Seya, Kazuhiko; Matsumiya, Tomoh; Sasaki, Eiji; Sasaki, Norihiro; Uesato, Ryoko; Ishibashi, Yasuyuki.

Afiliación

Saruga T; Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562, Japan. suntatsurous@hirosaki-u.ac.jp.
Imaizumi T; Department of Vascular Biology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562, Japan.
Kawaguchi S; Department of Vascular Biology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562, Japan.
Seya K; Department of Vascular Biology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562, Japan.
Matsumiya T; Department of Vascular Biology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562, Japan.
Sasaki E; Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562, Japan.
Sasaki N; Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562, Japan.
Uesato R; Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562, Japan.
Ishibashi Y; Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562, Japan.

Mol Biol Rep ; 48(1): 425-433, 2021 Jan.

Article en En | MEDLINE | ID: mdl-33387195

Asunto(s)

Artritis Reumatoide/genética; Quimiocina CXCL10/genética; Helicasa Inducida por Interferón IFIH1/genética; Receptor Toll-Like 3/genética; Artritis Reumatoide/patología; Biomimética; Fibroblastos/metabolismo; Fibroblastos/patología; Regulación de la Expresión Génica/genética; Humanos; Inmunidad Innata/genética; Inflamación/genética; Inflamación/patología; Interferón beta/genética; ARN Bicatenario/genética; ARN Bicatenario/farmacología; Transducción de Señal/genética; Membrana Sinovial/metabolismo; Membrana Sinovial/patología; Sinoviocitos/metabolismo; Sinoviocitos/patología

Palabras clave

CXCL10; IFN-ß; MDA5; Rheumatoid arthritis; TLR3

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Receptor Toll-Like 3 / Quimiocina CXCL10 / Helicasa Inducida por Interferón IFIH1 Límite: Humans Idioma: En Revista: Mol Biol Rep Año: 2021 Tipo del documento: Article País de afiliación: Japón

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