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Consult and procedure incidence outcomes following establishment of a fertility preservation program for children with cancer.
Behl, Supriya; Joshi, Vidhu B; Hussein, Reda S; Walker, David L; Lampat, Kari L; Krenik, Anthony G; Barud, Kathrynne M; Fredrickson, Jolene R; Galanits, Terri M; Rian, Katherine J; Delgado, Adriana M; Byrne, Julia H; Potter, Dean; Pittock, Siobhan T; Arndt, Carola A S; Zhao, Yulian; Gargollo, Patricio C; Granberg, Candace F; Khan, Zaraq; Chattha, Asma J.
Afiliación
  • Behl S; Children's Research Center, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
  • Joshi VB; Department of Urology, Mayo Clinic, Rochester, MN, USA.
  • Hussein RS; Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt.
  • Walker DL; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA.
  • Lampat KL; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA.
  • Krenik AG; Division of Pediatric and Adolescent Gynecology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.
  • Barud KM; In Vitro Fertilization Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
  • Fredrickson JR; In Vitro Fertilization Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
  • Galanits TM; In Vitro Fertilization Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
  • Rian KJ; In Vitro Fertilization Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
  • Delgado AM; In Vitro Fertilization Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
  • Byrne JH; Children's Research Center, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
  • Potter D; Children's Research Center, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
  • Pittock ST; Division of Pediatric Surgery, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
  • Arndt CAS; Division of Pediatric Endocrinology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
  • Zhao Y; Division of Pediatric Hematology and Oncology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
  • Gargollo PC; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA.
  • Granberg CF; In Vitro Fertilization Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
  • Khan Z; Department of Urology, Mayo Clinic, Rochester, MN, USA.
  • Chattha AJ; Department of Urology, Mayo Clinic, Rochester, MN, USA.
J Assist Reprod Genet ; 38(2): 495-501, 2021 Feb.
Article en En | MEDLINE | ID: mdl-33389381
PURPOSE: Fertility is a quality of life outcome adversely affected by cancer therapy. Many childhood cancer patients, however, are not offered options to preserve their fertility. Providers acknowledge difficulty discussing impaired fertility to patients due to lack of knowledge of available options. Our objective was to review the impact of a pediatric multidisciplinary fertility preservation program on providers' fertility preservation counseling and discussion of options. METHODS: A retrospective medical chart review was conducted for pediatric cancer patients prior to and following program establishment. Fertility preservation discussions, consults, and incidence were noted. Following filtering and stratification, 198 and 237 patients were seen prior to and following program establishment, respectively. RESULTS: Following program establishment, provider-patient discussions of impaired fertility (p = 0.007), fertility preservation consults (p = 0.01), and incidence of fertility preservation procedures (p < 0.001) increased among patients. Furthermore, the number of patients who received fertility preservation consults after receiving gonadotoxic treatment decreased (p < 0.001). This trend was particularly noted in pre-pubertal and female patients, for whom fertility preservation options are limited without an established program. CONCLUSION: The establishment of a formal program greatly improved access to fertility preservation consults and procedures in children with cancer.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Preservación de la Fertilidad / Supervivientes de Cáncer / Infertilidad / Neoplasias Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Qualitative_research / Risk_factors_studies Límite: Child / Female / Humans Idioma: En Revista: J Assist Reprod Genet Asunto de la revista: GENETICA / MEDICINA REPRODUTIVA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Preservación de la Fertilidad / Supervivientes de Cáncer / Infertilidad / Neoplasias Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Qualitative_research / Risk_factors_studies Límite: Child / Female / Humans Idioma: En Revista: J Assist Reprod Genet Asunto de la revista: GENETICA / MEDICINA REPRODUTIVA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos