Reversal of apolipoprotein E4-dependent or chemical-induced accumulation of APP degradation products by vitamin C-induced release of heparan sulfate from glypican-1.

Cheng, Fang; Fransson, Lars-Åke; Mani, Katrin

Cheng, Fang; Fransson, Lars-Åke; Mani, Katrin.

Afiliación

Cheng F; Department of Experimental Medical Science, Division of Neuroscience, Glycobiology Group, Lund University, Biomedical Center A13, SE-221 84 Lund, Sweden.
Fransson LÅ; Department of Experimental Medical Science, Division of Neuroscience, Glycobiology Group, Lund University, Biomedical Center A13, SE-221 84 Lund, Sweden.
Mani K; Department of Experimental Medical Science, Division of Neuroscience, Glycobiology Group, Lund University, Biomedical Center A13, SE-221 84 Lund, Sweden.

Glycobiology ; 31(7): 800-811, 2021 08 07.

Article en En | MEDLINE | ID: mdl-33403386

Asunto(s)

Enfermedad de Alzheimer; Glipicanos; Péptidos beta-Amiloides/metabolismo; Apolipoproteína E4/genética; Ácido Ascórbico/farmacología; Glipicanos/metabolismo; Heparitina Sulfato/metabolismo; Humanos

Palabras clave

Alzheimer's disease; apolipoprotein E; glypican-1; heparan sulfate; vitamin C

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Glipicanos / Enfermedad de Alzheimer Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Glycobiology Asunto de la revista: BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Suecia

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