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Genetic deletion of Polo-like kinase 2 reduces alpha-synuclein serine-129 phosphorylation in presynaptic terminals but not Lewy bodies.
Weston, Leah J; Stackhouse, Teresa L; Spinelli, Kateri J; Boutros, Sydney W; Rose, Elizabeth P; Osterberg, Valerie R; Luk, Kelvin C; Raber, Jacob; Weissman, Tamily A; Unni, Vivek K.
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  • Weston LJ; Department of Neurology & Jungers Center for Neurosciences Research, Oregon Health & Science University, Portland, Oregon, USA.
  • Stackhouse TL; Department of Neurology & Jungers Center for Neurosciences Research, Oregon Health & Science University, Portland, Oregon, USA.
  • Spinelli KJ; Department of Neurology & Jungers Center for Neurosciences Research, Oregon Health & Science University, Portland, Oregon, USA.
  • Boutros SW; Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, Oregon, USA.
  • Rose EP; Department of Neurology & Jungers Center for Neurosciences Research, Oregon Health & Science University, Portland, Oregon, USA; Neuroscience Graduate Program, Vollum Institute, Oregon Health & Science University, Portland, Oregon, USA.
  • Osterberg VR; Department of Neurology & Jungers Center for Neurosciences Research, Oregon Health & Science University, Portland, Oregon, USA.
  • Luk KC; Department of Pathology and Laboratory Medicine and Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
  • Raber J; Departments of Behavioral Neuroscience, Neurology, and Radiation Medicine and Division of Neuroscience, ONPRC, Oregon Health & Science University, Portland, Oregon, USA.
  • Weissman TA; Department of Biology, Lewis & Clark College, Portland, Oregon, USA.
  • Unni VK; Department of Neurology & Jungers Center for Neurosciences Research, Oregon Health & Science University, Portland, Oregon, USA; OHSU Parkinson Center, Oregon Health & Science University, Portland, Oregon, USA. Electronic address: unni@ohsu.edu.
J Biol Chem ; 296: 100273, 2021.
Article en En | MEDLINE | ID: mdl-33428941
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cuerpos de Lewy / Proteínas Serina-Treonina Quinasas / Terminales Presinápticos / Alfa-Sinucleína Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cuerpos de Lewy / Proteínas Serina-Treonina Quinasas / Terminales Presinápticos / Alfa-Sinucleína Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos