Resistance to Cyp3a induction by polychlorinated biphenyls, including non-dioxin-like PCB153, in gills of killifish (Fundulus heteroclitus) from New Bedford Harbor.

Celander, Malin C; Goldstone, Jared V; Brun, Nadja R; Clark, Bryan; Jayaraman, Saro; Nacci, Diane; Stegeman, John J

Celander, Malin C; Goldstone, Jared V; Brun, Nadja R; Clark, Bryan; Jayaraman, Saro; Nacci, Diane; Stegeman, John J.

Afiliación

Celander MC; Department of Biological and Environmental Sciences, University of Gothenburg, Box 463, SE 405 30, Gothenburg, Sweden; Biology Department, MS #32, Woods Hole Oceanographic Institution, Woods Hole, MA, 02543, USA. Electronic address: malin.celander@gu.se.
Goldstone JV; Biology Department, MS #32, Woods Hole Oceanographic Institution, Woods Hole, MA, 02543, USA.
Brun NR; Biology Department, MS #32, Woods Hole Oceanographic Institution, Woods Hole, MA, 02543, USA.
Clark B; United States Environmental Protection Agency, Office of Research and Development, Center for Environmental Measurement and Modeling, Atlantic Coastal Environmental Sciences Division, 27 Tarzwell Drive, Narragansett, RI, 02882, USA.
Jayaraman S; United States Environmental Protection Agency, Office of Research and Development, Center for Environmental Measurement and Modeling, Atlantic Coastal Environmental Sciences Division, 27 Tarzwell Drive, Narragansett, RI, 02882, USA.
Nacci D; United States Environmental Protection Agency, Office of Research and Development, Center for Environmental Measurement and Modeling, Atlantic Coastal Environmental Sciences Division, 27 Tarzwell Drive, Narragansett, RI, 02882, USA.
Stegeman JJ; Biology Department, MS #32, Woods Hole Oceanographic Institution, Woods Hole, MA, 02543, USA.

Environ Toxicol Pharmacol ; 83: 103580, 2021 Apr.

Article en En | MEDLINE | ID: mdl-33429071

Asunto(s)

Citocromo P-450 CYP3A/biosíntesis; Proteínas de Peces/biosíntesis; Fundulidae; Bifenilos Policlorados/toxicidad; Contaminantes Químicos del Agua/toxicidad; Animales; Citocromo P-450 CYP1A1/genética; Citocromo P-450 CYP3A/genética; Tolerancia a Medicamentos; Inducción Enzimática; Femenino; Proteínas de Peces/genética; Fundulidae/genética; Fundulidae/metabolismo; Branquias/efectos de los fármacos; Branquias/metabolismo; Hígado/efectos de los fármacos; Hígado/metabolismo; Masculino; Receptor X de Pregnano/genética; ARN Mensajero/metabolismo

Palabras clave

Cyp3a; Fish; Gills; PCB153; Resistance

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Contaminantes Químicos del Agua / Bifenilos Policlorados / Fundulidae / Proteínas de Peces / Citocromo P-450 CYP3A Límite: Animals Idioma: En Revista: Environ Toxicol Pharmacol Año: 2021 Tipo del documento: Article

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