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Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties.
Jiang, Bo; Luo, Jiao; Guo, Shuju; Wang, Lijun.
Afiliación
  • Jiang B; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, 7 Nanhai Road, Qingdao 266071, China.
  • Luo J; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
  • Guo S; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, 7 Nanhai Road, Qingdao 266071, China.
  • Wang L; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, 7 Nanhai Road, Qingdao 266071, China. Electronic address: wanglijun@qdio.ac.cn.
Bioorg Chem ; 108: 104648, 2021 03.
Article en En | MEDLINE | ID: mdl-33493928
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Experimental / Inhibidores Enzimáticos / Proteína Tirosina Fosfatasa no Receptora Tipo 1 / Descubrimiento de Drogas / Hipoglucemiantes Límite: Animals / Humans / Male Idioma: En Revista: Bioorg Chem Año: 2021 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Experimental / Inhibidores Enzimáticos / Proteína Tirosina Fosfatasa no Receptora Tipo 1 / Descubrimiento de Drogas / Hipoglucemiantes Límite: Animals / Humans / Male Idioma: En Revista: Bioorg Chem Año: 2021 Tipo del documento: Article País de afiliación: China