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Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition.
Cohen-Sharir, Yael; McFarland, James M; Abdusamad, Mai; Marquis, Carolyn; Bernhard, Sara V; Kazachkova, Mariya; Tang, Helen; Ippolito, Marica R; Laue, Kathrin; Zerbib, Johanna; Malaby, Heidi L H; Jones, Andrew; Stautmeister, Lisa-Marie; Bockaj, Irena; Wardenaar, René; Lyons, Nicholas; Nagaraja, Ankur; Bass, Adam J; Spierings, Diana C J; Foijer, Floris; Beroukhim, Rameen; Santaguida, Stefano; Golub, Todd R; Stumpff, Jason; Storchová, Zuzana; Ben-David, Uri.
Afiliación
  • Cohen-Sharir Y; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • McFarland JM; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Abdusamad M; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Marquis C; Department of Molecular Physiology and Biophysics, University of Vermont, Burlington, VT, USA.
  • Bernhard SV; Department of Molecular Genetics, TU Kaiserlautern, Kaiserlautern, Germany.
  • Kazachkova M; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Tang H; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Ippolito MR; Department of Experimental Oncology at IEO, European Institute of Oncology IRCCS, Milan, Italy.
  • Laue K; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Zerbib J; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Malaby HLH; Department of Molecular Physiology and Biophysics, University of Vermont, Burlington, VT, USA.
  • Jones A; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Stautmeister LM; Department of Molecular Genetics, TU Kaiserlautern, Kaiserlautern, Germany.
  • Bockaj I; European Research Institute for the Biology of Aging (ERIBA), University of Groningen, Groningen, The Netherlands.
  • Wardenaar R; European Research Institute for the Biology of Aging (ERIBA), University of Groningen, Groningen, The Netherlands.
  • Lyons N; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Nagaraja A; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Bass AJ; Dana Farber Cancer Institute, Boston, MA, USA.
  • Spierings DCJ; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Foijer F; Dana Farber Cancer Institute, Boston, MA, USA.
  • Beroukhim R; European Research Institute for the Biology of Aging (ERIBA), University of Groningen, Groningen, The Netherlands.
  • Santaguida S; European Research Institute for the Biology of Aging (ERIBA), University of Groningen, Groningen, The Netherlands.
  • Golub TR; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Stumpff J; Dana Farber Cancer Institute, Boston, MA, USA.
  • Storchová Z; Department of Experimental Oncology at IEO, European Institute of Oncology IRCCS, Milan, Italy.
  • Ben-David U; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
Nature ; 590(7846): 486-491, 2021 02.
Article en En | MEDLINE | ID: mdl-33505028
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Puntos de Control de la Fase M del Ciclo Celular / Aneuploidia / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: Israel
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Puntos de Control de la Fase M del Ciclo Celular / Aneuploidia / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: Israel