ILC1: guardians of the oral mucosa against enemy viruses.

Nabekura, Tsukasa; Shibuya, Akira

Nabekura, Tsukasa; Shibuya, Akira.

Afiliación

Nabekura T; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan; Department of Immunology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan; R&D Center for Innovative Drug Discovery, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Shibuya A; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan; Department of Immunology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan; R&D Center for Innovative Drug Discovery, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan. Electronic address: ashibuya@md.tsukuba.ac.jp.

Immunity ; 54(2): 196-198, 2021 02 09.

Article en En | MEDLINE | ID: mdl-33567258

ABSTRACT

ABSTRACT

Type 1 innate lymphoid cells (ILC1s) regulate inflammation in the tissues; however, their role in anti-viral immunity remains largely unknown. In this issue of Immunity, Shannon et al. report that ILC1s invoke an anti-viral effect by producing interferon (IFN)Î³ at homeostasis, thereby limiting viral replication in the oral mucosa.

Asunto(s)

Linfocitos; Virus; Humanos; Inmunidad Innata; Inflamación; Mucosa Bucal

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Virus / Linfocitos Límite: Humans Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Japón

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