In Esophageal Squamous Cells From Eosinophilic Esophagitis Patients, Th2 Cytokines Increase Eotaxin-3 Secretion Through Effects on Intracellular Calcium and a Non-Gastric Proton Pump.

Odiase, Eunice; Zhang, Xi; Chang, Yan; Nelson, Melissa; Balaji, Uthra; Gu, Jinghua; Zhang, Qiuyang; Pan, Zui; Spechler, Stuart Jon; Souza, Rhonda F

Odiase, Eunice; Zhang, Xi; Chang, Yan; Nelson, Melissa; Balaji, Uthra; Gu, Jinghua; Zhang, Qiuyang; Pan, Zui; Spechler, Stuart Jon; Souza, Rhonda F.

Afiliación

Odiase E; Department of Medicine, Center for Esophageal Diseases, Baylor University Medical Center and Center for Esophageal Research, Baylor Scott & White Research Institute, Dallas, Texas; Department of Pediatrics, Children's Hospital of Colorado, Aurora, Colorado.
Zhang X; Department of Medicine, Center for Esophageal Diseases, Baylor University Medical Center and Center for Esophageal Research, Baylor Scott & White Research Institute, Dallas, Texas.
Chang Y; College of Nursing and Health Innovation, University of Texas at Arlington, Arlington, Texas.
Nelson M; Department of Medicine, Center for Esophageal Diseases, Baylor University Medical Center and Center for Esophageal Research, Baylor Scott & White Research Institute, Dallas, Texas.
Balaji U; Biostatistics Core, Baylor Scott & White Research Institute, Dallas, Texas.
Gu J; Biostatistics Core, Baylor Scott & White Research Institute, Dallas, Texas.
Zhang Q; Department of Medicine, Center for Esophageal Diseases, Baylor University Medical Center and Center for Esophageal Research, Baylor Scott & White Research Institute, Dallas, Texas.
Pan Z; College of Nursing and Health Innovation, University of Texas at Arlington, Arlington, Texas.
Spechler SJ; Department of Medicine, Center for Esophageal Diseases, Baylor University Medical Center and Center for Esophageal Research, Baylor Scott & White Research Institute, Dallas, Texas.
Souza RF; Department of Medicine, Center for Esophageal Diseases, Baylor University Medical Center and Center for Esophageal Research, Baylor Scott & White Research Institute, Dallas, Texas. Electronic address: rhonda.souza@BSWHealth.org.

Gastroenterology ; 160(6): 2072-2088.e6, 2021 05.

Article en En | MEDLINE | ID: mdl-33581123

Asunto(s)

Quimiocina CCL26/metabolismo; Esofagitis Eosinofílica/metabolismo; Esofagitis Eosinofílica/patología; Células Epiteliales/metabolismo; ATPasa Intercambiadora de Hidrógeno-Potásio/genética; ATPasa Intercambiadora de Hidrógeno-Potásio/metabolismo; Transporte Biológico/efectos de los fármacos; Compuestos de Boro/farmacología; Calcio/metabolismo; Bloqueadores de los Canales de Calcio/farmacología; Línea Celular; Diltiazem/farmacología; Ácido Egtácico/análogos & derivados; Ácido Egtácico/farmacología; Mucosa Esofágica/metabolismo; Mucosa Esofágica/patología; Famotidina/farmacología; Femenino; Antagonistas de los Receptores H2 de la Histamina/farmacología; Humanos; Subunidad alfa del Receptor de Interleucina-4/metabolismo; Masculino; Omeprazol/farmacología; Cultivo Primario de Células; Inhibidores de la Bomba de Protones/farmacología; Bombas de Protones/efectos de los fármacos; Bombas de Protones/metabolismo; ARN Mensajero/metabolismo; Ranitidina/farmacología; Transducción de Señal/efectos de los fármacos; Células Th2/metabolismo; Verapamilo/farmacología

Palabras clave

Diltiazem; Potassium-Competitive Acid Blockers; Proton Pump Inhibitors; Verapamil

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ATPasa Intercambiadora de Hidrógeno-Potásio / Células Epiteliales / Esofagitis Eosinofílica / Quimiocina CCL26 Límite: Female / Humans / Male Idioma: En Revista: Gastroenterology Año: 2021 Tipo del documento: Article

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