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First-in-human, phase I/IIa study of CRLX301, a nanoparticle drug conjugate containing docetaxel, in patients with advanced or metastatic solid malignancies.
Piha-Paul, Sarina A; Thein, Kyaw Z; De Souza, Paul; Kefford, Richard; Gangadhar, Tara; Smith, Christopher; Schuster, Shelly; Zamboni, William C; Dees, Claire E; Markman, Ben.
Afiliación
  • Piha-Paul SA; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA. spihapau@mdanderson.org.
  • Thein KZ; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.
  • De Souza P; Division of Hematology and Medical Oncology, Oregon Health and Science University/ Knight Cancer Institute, Portland, OR, USA.
  • Kefford R; Department of Medical Oncology, Liverpool Hospital, Sydney, Australia.
  • Gangadhar T; Department of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
  • Smith C; Department of Hematology and Medical Oncology, University of Pennsylvania, Philadelphia, PA, USA.
  • Schuster S; NewLink Genetics Corporation, Ames, IA, USA.
  • Zamboni WC; NewLink Genetics Corporation, Ames, IA, USA.
  • Dees CE; UNC Eshelman School of Pharmacy, UNC Lineberger Comprehensive Cancer Center, Carolina Institute of Nanomedicine, Chapel Hill, NC, USA.
  • Markman B; Division of Medical Oncology, University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.
Invest New Drugs ; 39(4): 1047-1056, 2021 08.
Article en En | MEDLINE | ID: mdl-33594602

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Nanopartículas / Docetaxel / Neoplasias / Antineoplásicos Tipo de estudio: Clinical_trials Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Nanopartículas / Docetaxel / Neoplasias / Antineoplásicos Tipo de estudio: Clinical_trials Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos