Adaptive and Constitutive Activations of Malic Enzymes Confer Liver Cancer Multilayered Protection Against Reactive Oxygen Species.

Lee, Derek; Zhang, Misty Shuo; Tsang, Felice Ho-Ching; Bao, Macus Hao-Ran; Xu, Iris Ming-Jing; Lai, Robin Kit-Ho; Chiu, David Kung-Chun; Tse, Aki Pui-Wah; Law, Cheuk-Ting; Chan, Cerise Yuen-Ki; Yuen, Vincent Wai-Hin; Chui, Noreen Nog-Qin; Ng, Irene Oi-Lin; Wong, Chun-Ming; Wong, Carmen Chak-Lui

Lee, Derek; Zhang, Misty Shuo; Tsang, Felice Ho-Ching; Bao, Macus Hao-Ran; Xu, Iris Ming-Jing; Lai, Robin Kit-Ho; Chiu, David Kung-Chun; Tse, Aki Pui-Wah; Law, Cheuk-Ting; Chan, Cerise Yuen-Ki; Yuen, Vincent Wai-Hin; Chui, Noreen Nog-Qin; Ng, Irene Oi-Lin; Wong, Chun-Ming; Wong, Carmen Chak-Lui.

Afiliación

Lee D; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Zhang MS; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Tsang FH; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Bao MH; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Xu IM; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Lai RK; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Chiu DK; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Tse AP; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Law CT; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Chan CY; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Yuen VW; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Chui NN; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Ng IO; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.
Wong CM; State Key Laboratory of Liver ResearchThe University of Hong KongHong KongHong Kong.
Wong CC; Department of PathologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongHong Kong.

Hepatology ; 74(2): 776-796, 2021 08.

Article en En | MEDLINE | ID: mdl-33619771

Asunto(s)

Carcinoma Hepatocelular/patología; Neoplasias Hepáticas/patología; Malato Deshidrogenasa/genética; Oxidorreductasas de Alcohol Dependientes de NAD (+) y NADP (+)/genética; Factor 2 Relacionado con NF-E2/metabolismo; Animales; Carcinoma Hepatocelular/genética; Línea Celular Tumoral; Regulación Neoplásica de la Expresión Génica; Técnicas de Silenciamiento del Gen; Hepatocitos; Humanos; Proteína 1 Asociada A ECH Tipo Kelch/metabolismo; Neoplasias Hepáticas/genética; Malato Deshidrogenasa/metabolismo; Metabolómica; Ratones; Oxidorreductasas de Alcohol Dependientes de NAD (+) y NADP (+)/metabolismo; Estrés Oxidativo/genética; Especies Reactivas de Oxígeno/metabolismo; Activación Transcripcional; Ensayos Antitumor por Modelo de Xenoinjerto

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Factor 2 Relacionado con NF-E2 / Oxidorreductasas de Alcohol Dependientes de NAD (/) y NADP (/) / Neoplasias Hepáticas / Malato Deshidrogenasa Tipo de estudio: Observational_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Hepatology Año: 2021 Tipo del documento: Article

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