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Serological Profiling of Group A Streptococcus Infections in Acute Rheumatic Fever.
Lorenz, Natalie; Ho, Timothy K C; McGregor, Reuben; Davies, Mark R; Williamson, Deborah A; Gurney, Jason K; Smeesters, Pierre R; Baker, Michael G; Moreland, Nicole J.
Afiliación
  • Lorenz N; School of Medical Sciences, University of Auckland, Auckland, New Zealand.
  • Ho TKC; Maurice Wilkins Centre for Biodiscovery, Auckland, New Zealand.
  • McGregor R; School of Medical Sciences, University of Auckland, Auckland, New Zealand.
  • Davies MR; School of Medical Sciences, University of Auckland, Auckland, New Zealand.
  • Williamson DA; Maurice Wilkins Centre for Biodiscovery, Auckland, New Zealand.
  • Gurney JK; Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Australia.
  • Smeesters PR; Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Australia.
  • Baker MG; Department of Public Health, University of Otago, Wellington, New Zealand.
  • Moreland NJ; Molecular Bacteriology Laboratory, Université Libre de Bruxelles, Brussels, Belgium.
Clin Infect Dis ; 73(12): 2322-2325, 2021 12 16.
Article en En | MEDLINE | ID: mdl-33639619
ABSTRACT
Rheumatic fever is a serious post-infectious sequela of group A Streptococcus (GAS). Prior GAS exposures were mapped in sera using a large panel of M-type specific peptides. Rheumatic fever patients had serological evidence of significantly more GAS exposures than matched controls suggesting immune priming by repeat infections contributes to pathogenesis.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fiebre Reumática / Infecciones Estreptocócicas Límite: Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2021 Tipo del documento: Article País de afiliación: Nueva Zelanda

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fiebre Reumática / Infecciones Estreptocócicas Límite: Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2021 Tipo del documento: Article País de afiliación: Nueva Zelanda