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Breast Cancer Research to Support Evidence-Based Medicine in Nigeria: A Review of the Literature.
Fatiregun, Omolara A; Oluokun, Temiloluwa; Lasebikan, Nwamaka N; Nwachukwu, Emmanuella; Ibraheem, Abiola A; Olopade, Olufunmilayo.
Afiliación
  • Fatiregun OA; Department of Radiology, Oncology Unit, Lagos State University College of Medicine, Lagos, Nigeria.
  • Oluokun T; University of Liverpool School of Medicine, Liverpool, United Kingdom.
  • Lasebikan NN; Department of Radiation Medicine, University of Nigeria Teaching Hospital, Enugu, Nigeria.
  • Nwachukwu E; Department of Radiotherapy and Oncology, National Hospital Abuja, Abuja, Nigeria.
  • Ibraheem AA; Department of Medicine, University of Chicago, Chicago, IL.
  • Olopade O; Centre for Clinical Cancer Genetics and Global Health, University of Chicago, Chicago, IL.
JCO Glob Oncol ; 7: 384-390, 2021 03.
Article en En | MEDLINE | ID: mdl-33720754
ABSTRACT

PURPOSE:

Breast cancer is the most common malignancy in women worldwide. In Nigeria, it accounts for 22.7% of all new cancer cases among women. Evidence-based medicine (EBM) entails using the results from healthcare research to enhance the clinical decision-making process and develop evidence-based treatment guidelines. Level 1 and 2 studies, such as randomized controlled trials, meta-analyses, and systematic reviews of randomized controlled trials, yield more robust types of evidence. This study reviewed the levels of evidence of breast cancer publications in Nigeria.

METHODS:

We conducted an electronic literature search of all studies published on breast cancer in Nigeria from January 1961 to August 2019. We reviewed all the articles found under the search term "Breast Cancer in Nigeria" on medical databases.

RESULTS:

Our search identified 2,242 publications. One thousand two hundred fifty duplicates were removed, and 520 were excluded. A total of 472 articles were considered eligible for this review. Most of these articles were case series or reports (30.7%), qualitative studies (15.7%), followed by cross-sectional studies (13.3%), laboratory studies (12.9%), case-control studies (6.1%), case reports (7%), and cohort (5.7%).

CONCLUSION:

Breast cancer research in Nigeria is yet to produce much evidence of the types considered to best support EBM. The scarcity of data hampers the implementation of EBM in Nigeria. Currently, most treatment guidelines are adapted from those developed in other countries, despite genetic differences among populations and different environmental influencing factors.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama Tipo de estudio: Clinical_trials / Guideline / Observational_studies / Prevalence_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies / Systematic_reviews Límite: Female / Humans País/Región como asunto: Africa Idioma: En Revista: JCO Glob Oncol Año: 2021 Tipo del documento: Article País de afiliación: Nigeria

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama Tipo de estudio: Clinical_trials / Guideline / Observational_studies / Prevalence_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies / Systematic_reviews Límite: Female / Humans País/Región como asunto: Africa Idioma: En Revista: JCO Glob Oncol Año: 2021 Tipo del documento: Article País de afiliación: Nigeria