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Structure, interdomain dynamics, and pH-dependent autoactivation of pro-rhodesain, the main lysosomal cysteine protease from African trypanosomes.
Johé, Patrick; Jaenicke, Elmar; Neuweiler, Hannes; Schirmeister, Tanja; Kersten, Christian; Hellmich, Ute A.
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  • Johé P; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Mainz, Germany.
  • Jaenicke E; Institute for Molecular Physiology, Johannes Gutenberg-University, Mainz, Germany.
  • Neuweiler H; Department for Biotechnology and Biophysics, Julius-Maximilians-University, Würzburg, Germany.
  • Schirmeister T; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Mainz, Germany.
  • Kersten C; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Mainz, Germany. Electronic address: kerstec@uni-mainz.de.
  • Hellmich UA; Department of Chemistry, Biochemistry Division, Johannes Gutenberg-University, Mainz, Germany; Centre for Biomolecular Magnetic Resonance (BMRZ), Goethe University, Frankfurt, Germany. Electronic address: ute.hellmich@uni-jena.de.
J Biol Chem ; 296: 100565, 2021.
Article en En | MEDLINE | ID: mdl-33745969
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cisteína Endopeptidasas / Trypanosoma brucei rhodesiense / Precursores Enzimáticos Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cisteína Endopeptidasas / Trypanosoma brucei rhodesiense / Precursores Enzimáticos Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: Alemania