Cancer-associated fibroblasts induce an aggressive phenotypic shift in non-malignant breast epithelial cells via interleukin-8 and S100A8.

Lim, Hyesol; Koh, Minsoo; Jin, Hao; Bae, Mijeong; Lee, Seung-Yeon; Kim, Kyoung Mee; Jung, Joohee; Kim, Hyun Jeong; Park, So Yeon; Kim, Hoe Suk; Moon, Woo Kyung; Hwang, Sejin; Cho, Nam Hoon; Moon, Aree

Lim, Hyesol; Koh, Minsoo; Jin, Hao; Bae, Mijeong; Lee, Seung-Yeon; Kim, Kyoung Mee; Jung, Joohee; Kim, Hyun Jeong; Park, So Yeon; Kim, Hoe Suk; Moon, Woo Kyung; Hwang, Sejin; Cho, Nam Hoon; Moon, Aree.

Afiliación

Lim H; Duksung Innovative Drug Center, College of Pharmacy, Duksung Women's University, Seoul, Korea.
Koh M; Duksung Innovative Drug Center, College of Pharmacy, Duksung Women's University, Seoul, Korea.
Jin H; Duksung Innovative Drug Center, College of Pharmacy, Duksung Women's University, Seoul, Korea.
Bae M; Duksung Innovative Drug Center, College of Pharmacy, Duksung Women's University, Seoul, Korea.
Lee SY; Duksung Innovative Drug Center, College of Pharmacy, Duksung Women's University, Seoul, Korea.
Kim KM; Duksung Innovative Drug Center, College of Pharmacy, Duksung Women's University, Seoul, Korea.
Jung J; Duksung Innovative Drug Center, College of Pharmacy, Duksung Women's University, Seoul, Korea.
Kim HJ; Department of Pathology, Seoul National University Bundang Hospital, Gyeonggi, Korea.
Park SY; Department of Pathology, Seoul National University Bundang Hospital, Gyeonggi, Korea.
Kim HS; Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
Moon WK; Department of Radiology, Seoul National University Hospital, Seoul, Korea.
Hwang S; Department of Radiology, Seoul National University Hospital, Seoul, Korea.
Cho NH; Department of Anatomy and Cell Biology, College of Medicine, Hanyang University, Seoul, Korea.
Moon A; Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

J Cell Physiol ; 236(10): 7014-7032, 2021 10.

Article en En | MEDLINE | ID: mdl-33748944

Asunto(s)

Neoplasias de la Mama/metabolismo; Calgranulina A/metabolismo; Fibroblastos Asociados al Cáncer/metabolismo; Células Epiteliales/metabolismo; Interleucina-8/metabolismo; Comunicación Paracrina; Animales; Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/genética; Neoplasias de la Mama/patología; Proteína beta Potenciadora de Unión a CCAAT/genética; Proteína beta Potenciadora de Unión a CCAAT/metabolismo; Calgranulina A/genética; Fibroblastos Asociados al Cáncer/efectos de los fármacos; Fibroblastos Asociados al Cáncer/patología; Línea Celular Tumoral; Movimiento Celular; Técnicas de Cocultivo; Células Epiteliales/patología; Transición Epitelial-Mesenquimal; Femenino; Humanos; Interleucina-8/genética; Ratones Endogámicos BALB C; Ratones Desnudos; Invasividad Neoplásica; Fenotipo; Transducción de Señal; Sulfonamidas/farmacología; Factor de Transcripción ReIA/genética; Factor de Transcripción ReIA/metabolismo; Células Tumorales Cultivadas; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

S100A8; breast cancer; cancer-associated fibroblasts; interleukin-8; invasion

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Interleucina-8 / Comunicación Paracrina / Calgranulina A / Células Epiteliales / Fibroblastos Asociados al Cáncer Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: J Cell Physiol Año: 2021 Tipo del documento: Article

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