The relationship of neurodevelopmental impairment to concurrent early childhood outcomes of extremely preterm infants.
J Perinatol
; 41(9): 2270-2278, 2021 09.
Article
en En
| MEDLINE
| ID: mdl-33758389
ABSTRACT
OBJECTIVE:
Determine how neurodevelopmental impairment (NDI) relates to concurrent outcomes for children born extremely preterm. STUDYDESIGN:
Retrospective cohort study children born 22 0/7-26 6/7 weeks' gestation at NICHD Neonatal Research Network hospitals. Outcomes were ascertained at 18-22 months' corrected age.RESULT:
Of 6562 children, 2618 (40%) died and 441 (7%) had no follow-up. Among the remaining 3483 children, 825 (24%), 1576 (45%), 657 (19%), and 425 (12%) had no, potential/mild, moderate, and severe NDI, respectively. Rehospitalization, respiratory medications, surgery, and medical support services were associated with greater NDI severity but affected >10% of children without NDI. Rehospitalization occurred in 40% of children with no NDI (mean (SD) 1.7 (1.3) episodes).CONCLUSION:
Medical, functional, and social outcomes at 18-22 months' corrected age were associated with NDI; however, many children without NDI were affected. These data should contribute to counseling families and the design of studies for childhood outcomes beyond NDI.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Trastornos del Neurodesarrollo
/
Enfermedades del Prematuro
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Child
/
Child, preschool
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Humans
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Infant
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Newborn
Idioma:
En
Revista:
J Perinatol
Asunto de la revista:
PERINATOLOGIA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Estados Unidos